300 gr bullet at 1850 is good for a shade over 2200 ft lbs of energy. According the ballistics drop chart They are still super sonic at 275 and drop subsonic between 275 and 300. so limit your shots to 275 and closer as the bullets will most likely go unstable as they drop sub sonic. and at 275 with a velocity of about 1100 fps they are still hitting with a shade over 800 ft lbs of energy. or pretty much a .44 magnum at point blank. so yeah.. theyll drop deer like a sack of taters out to 275 with good accuracy.. according to the math of course..