Originally Posted by Bindernut
For me the choice is clear. If I was down to only keeping one rifle, I'd keep the .243.
The .243 (and/or 6mmRem) was my dual-purpose yote/deer rifle for a few years. Works great for either critter even with the same load (100gr SP).
Yeah I've hunted yotes with dad's .270 (and my .25-06) but they're not the best hide-hunting cartridges. But it's tops for whitetails and plenty good enough for elk too unless you're trying to take shots clear into the next county.
So...Keep em both and expand your ammo selection.
-75gr HP for prairie dogs
-100/105gr SP (or 90gr Barnes TSX/TTSX) for coyotes and whitetails
-130gr Barnes TSX for coyotes. (It works darn near like a FMJ...very little expansion on yotes. Two small holes in the hide, both easily stitchable.)
-130gr or 140gr for whitetails.
-140gr or 150gr for elk.
-150gr Barnes TSX or 160gr Nosler Partition if you really need a thumper for big deer (elk/moose/etc)
You can hold off on the .22-250 and .300Mag for a few years this way.
Pretty good advise but i will disagree just a bit.
I would take the 243 now and hunt deer and yotes. I would pass on the 270 because honestly if your gona get a 300 mag then you will probably never use the 270 again. I would pass on the 22 250 also if you allready have a 243. With a 243 and a 300 mag you have all the guns you will ever need. After that it is a matter of collecting.