Check out this site. http://www.gunsmoke.com/guns/1022/22ballistics.html
Subsonic ammunition is much more accurate than high velocity. If not, why is all the target ammunition subsonic? Lapua, Eley, RWS top of the line is subsonic.
Look at the ballistic tables. HV out to 100 yards is not that much flatter than SS.
Shooting targets at 100 yards with 22lr is a lot of fun. But shooting critters with a 22lr at 100 yards, UH UH, just not enough terminal energy for a clean kill. Yes, I know there are people that say they can do it, but at 100 yards plus, use at least a 22 mag, centerfire is much better.