Re: shotgun reloading question?
Don't throw it out, I would for sure separate them but just do small amounts of powder at a time and do the tedious task of picking out the shot. happens to the best of us, a little patience and you'll be good to go.
I doubt it would do much if any damage to the gun but not worth the risk to me, peace of mind really. A large piece of creased cardboard or similar, tilt it so the shot rolls down and blow the powder 'up' the incline (not too steep) or whatever other creative method you can imagine.
"Loud noises don't end gunfights.... well placed shots do."