How about a 458 JDJ in a Thomson Center. Not only will the muzzle blast get their attention, it will clean them too!
All kidding aside, the .308 in the Savage Striker comes to mind! A good 150 to 180 gr bullet will always do it's job! Also look at all the JDJ rounds if you reload. If not, stick with normal over the counter rounds.
Stay low and stay well, Ray.