velocity difference would be around 100 fps. with the longer barrel being faster. The .50 beowulf is a faster cartridge than the .44 mag, but performance is similar. Your targets prolly wont notice a difference
It takes 43 muscles to frown, 17 to smile, and 3 for proper trigger squeeze.
The latest caliber or gear is no substitute for experience and skill. Rifles and cartridges don't make hits -- shooters do.
Fact of life:
After Monday and Tuesday, even the calendar says WTF!