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Ive not ever used 4064 in a .243. I feel its a bit too fast for the heavier (than 85 gr) bullets.. I find superb accuracy and velocity with 4000MR under 85 Sierra GameKings and 105 Hdy Amaxes.
 

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+1 to Josh's post. I've used 4064 with 75gr loads but for my 100gr loads I prefer H4350 (IMR4350 will work too).
I've also used RL-19 for 100gr loads too but H4350 was always a bit more consistent in the velocity department for me.

4064 is a bit on the fast side, but if that's what you've got on the shelf it will work.
 
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