I luv TTSX's in my 6.8 (110 grain) and in my 30-378 (180 grain); use nosler partitions in everything else, 270, 7 mag, 338 fed, 338 win mag. Going to try TTSX's & TSX's in my 308 Scar soon as the snow melts. I chronoed my 30-378 with 98 grains RL-22 with 180 grain ttsx's and they were leaving the barrel at 3280. Friends use 165 or 168's with 104 grains RL-22 and get 3600, but that much just gives me a tight bolt.
We have killed a bunch of caribou over the years, at least a dozen bear, all with the 6.8 with blue tips. I don't have near the luck with accubond white tips, for whatever reason. Have killed quite a few moose with the 30-378 too, but prefer nosler partitions for moose so usually take another gun.
For whatever reason, I have become superstitious and swear by TTSX blue tips in two of my guns and I don't care what they cost. A buddy last year switched to GMX's hornadys due to cost and he had a few bear and caribou not go right down first shot; quit using the GMX's. I stick with what works for me.