bigdad5no. Its no different than leaving a magazine loaded. Springs don't wear out by being compressed. they wear out by being worked.
Hope those 1 / 2 rds ain't the death of youI agree with JLA not that he needs the support but he is correct about the main spring being compressed. And also about leaveing rounds in a Mag however even though i know deep down that leaveing rounds in a mag wont hunt it i alway leave 1 / 2 rounds out as a safety net for the mag spring.
While I agree that leaving it open does not hurt the spring, it does make it easier for dust and dirt and dog hair and assorted like crud to get into the innards. I store all my guns with the bolts closed.